@font-face {
  font-family: roboto;
  src: url(https://knowledgebase.microdiscovery.de/fonts/roboto-v20-latin-regular.ttf);
}

@font-face {
  font-family: Simple-Line-Icons;
  src: url(https://knowledgebase.microdiscovery.de/fonts/Simple-Line-Icons.ttf);
}

div.mainDiv {
	position: absolute;
	width: 100%;
	height: 100%;
	overflow: hidden;
	left: 0px;
	top:0px;
	font-family: roboto;
}
div.header {
	position: absolute;
	width: 100%;
	height: 80px;
	top: 0px;
	background-image: linear-gradient(to right, rgba(200,230,255,1),rgba(240,240,255,0.5), rgba(200,230,255,1));
	left: 0px;
	display: flex;
  	align-items: center;
  	justify-content: center;
}

div.heatmapContent {
	position: absolute;
	top: 200px;
	bottom: 0px;
	right:0px;
	left:0px;
	overflow: auto;
	margin-bottom:40px;
}

div.searchForm {
	position: absolute;
	top: 100px;
	height: 100px;
	right:0px;
	left:0px;
	display: flex;
  	align-items: center;
  	justify-content: center;
}

div.progressIndicatorOuter {
	position: absolute;
	left: calc(50% - 250px);
	top: calc(50% - 125px);
	width: 500px;
	height:250px;
	z-index: 2;
	text-align: center;
}

div.progressIndicator {
	position: absolute;
	left: calc(50% - 50px);
	top: calc(50% - 50px);
	width: 50px;
	height:150px;
	z-index: 2;
	text-align: center;
}

div.progressText {
	position: relative;
	height: 100px;
	top: 200px;
}

div.footer {
	position: absolute;
	z-index: 2;
	height: 20px;
	left: 0px;
	right: 0px;
	bottom: 0px;
	background-color: rgba(250,250,250,0.95);
	padding: 5px;
	text-align: right;
	border: 1px solid rgb(200,200,200);
	color: rgb(50,50,80);
}


div.progressC1 {
	position: relative;
    top: 0;
    left: 0;
    width: 100px;
    height: 100px;
    border: 5px solid transparent;
    border-top-color: #3498db; 
    z.index: 3;
    border-radius: 50%;
    -webkit-animation: spin 2s linear infinite;
    animation: spin 2s linear infinite;
    margin-bottom: 10px;
}

div.progressC2 {
	position: relative;
    top: 10px;
    left: 10px;
    width: 70px;
    height: 70px;
    border: 5px solid transparent;
    border-top-color: rgb(222,200,200); 
    z.index: 4;
    border-radius: 50%;
    -webkit-animation: spin 1.5s linear infinite;
    animation: spin 1.5s linear infinite;
}


@-webkit-keyframes spin {
    0%   {
        -webkit-transform: rotate(0deg);  /* Chrome, Opera 15+, Safari 3.1+ */
        -ms-transform: rotate(0deg);  /* IE 9 */
        transform: rotate(0deg);  /* Firefox 16+, IE 10+, Opera */
    }
    100% {
        -webkit-transform: rotate(360deg);  /* Chrome, Opera 15+, Safari 3.1+ */
        -ms-transform: rotate(360deg);  /* IE 9 */
        transform: rotate(360deg);  /* Firefox 16+, IE 10+, Opera */
    }
}
@keyframes spin {
    0%   {
        -webkit-transform: rotate(0deg);  /* Chrome, Opera 15+, Safari 3.1+ */
        -ms-transform: rotate(0deg);  /* IE 9 */
        transform: rotate(0deg);  /* Firefox 16+, IE 10+, Opera */
    }
    100% {
        -webkit-transform: rotate(360deg);  /* Chrome, Opera 15+, Safari 3.1+ */
        -ms-transform: rotate(360deg);  /* IE 9 */
        transform: rotate(360deg);  /* Firefox 16+, IE 10+, Opera */
    }
}

table.heatmap {
	position: absolute;
	top: 120px;
	background-color: white;
	border-collapse: collapse;
	cursor: default;
	font-weight: 600;
	padding-bottom: 30px;
}

td.header {
	transform: rotate(-90.0deg);
	padding-bottom: 100px;
}

td.entry {
	width: 50px;
	border: 1px solid rgb(200,200,200);
	text-align: center;
	font-size: 15px;
	font-weight: 100;
	color: rgb(40,40,90);
}

td.rowHeader {
	padding-left: 10px;
	color: rgb(90,90,140);
}

div.vertical{
  margin-left: -7px;
  margin-top: -100px;
  position: absolute;
  width: 215px;
  color: rgb(90,90,140);
  transform: rotate(-45deg);
  -webkit-transform: rotate(-45deg); /* Safari/Chrome */
  -moz-transform: rotate(-45deg);    /* Firefox */
  -o-transform: rotate(-45deg);      /* Opera */
  -ms-transform: rotate(-45deg);     /* IE 9 */
}

div.mouseover{
	position: absolute;
	width: 300px;
	height: 100px;
	background-color: rgb(245,220,200);
	border-radius: 10px;
	border: 1px solid grey;
	visibility: hidden;
}

div.mouseoverText{
	position: absolute;
	width: 300px;
	height: 100px;
	background-color: rgb(245,220,200);
	border-radius: 10px;
	border: 1px solid grey;
	visibility: hidden;
	padding: 15px;
	overflow: hidden;
	z-index: 5;
}

table.mouseover{
	padding: 10px;
}

div.popup {
	position: absolute;
	top: 80px;
	bottom: 30px;
	right: 0px;
	width: 100%;
	background: rgba(200,200,200,0.8);
	visibility: hidden;
	z-index: 1;
}

div.popupContent {
	position: absolute;
	top: 20px;
	bottom: 20px;
	right: 20px;
	left: 20px;
	background: white;
	border-radius: 10px;
	border: 1px solid grey;
	z-index: 2;
}

div.popupContentClose {
	position: absolute;
	top: 30px;
	right: 33px;
	width: 20px;
	height: 20px;
	z-index: 2;
	cursor: default;
	font-family: Simple-Line-Icons;
	font-size: 24px;
}

div.details {
	position: absolute;
	top: 20px;
	right: 20px;
	left: 20px;
	bottom: 20px;
	overflow: hidden;	
}

div.publications {
	position: absolute;
	top: 140px;
	bottom: 0px;
	right: 0px;
	left:0px;
	overflow: auto;
	border: 1px solid grey;
	border-radius: 10px;
	z-index: 4;
	background: white;
}

div.genes {
	position: absolute;
	top: 0px;
	bottom: 0px;
	left:0px;
	width: 800px;
	overflow: auto;
	border: 1px solid grey;
	border-radius: 10px;
}

div.interactions {
	position: absolute;
	top: 0px;
	bottom: 0px;
	left:0px;
	width:800px;
	overflow: auto;
	border: 1px solid grey;
	border-radius: 10px;
}

div.words {
	position: absolute;
	top: 0px;
	bottom: 0px;
	left:0px;
	width:800px;
	overflow: auto;
	border: 1px solid grey;
	border-radius: 10px;
}

div.similarCompounds {
	position: absolute;
	top: 0px;
	bottom: 0px;
	left:0px;
	width:800px;
	overflow: auto;
	border: 1px solid grey;
	border-radius: 10px;
}

table.publications {
	background-color: rgb(249,235,232);
	border: 0px;
  	padding: 0px;
  	margin: 0px;
  	border-collapse: collapse;
  	color: rgb(50,55,50);
  	width: 100%;
}

td.publicationsCell {
	border: 0px;
	border-top: 1px solid grey;
}

span.compound {
	background-color: rgb(230,100,100);
	color: white;
	margin-left: 5px;
	margin-right: 5px;
	padding-left: 5px;
	padding-right: 5px;
	border-radius: 5px;
	font-weight: 600;
}

span.cancer {
	background-color: rgb(100,100,200);
	color: white;
	margin-left: 5px;
	margin-right: 5px;
	padding-left: 5px;
	padding-right: 5px;
	border-radius: 5px;
	font-weight: 600;
}

span.cancerAD {
	background-color: rgb(130,130,200);
	color: white;
	margin-left: 5px;
	margin-right: 5px;
	padding-left: 5px;
	padding-right: 5px;
	border-radius: 5px;
	font-weight: 600;
}

span.gene {
	background-color: rgb(100,200,100);
	color: white;
	margin-left: 5px;
	margin-right: 5px;
	padding-left: 5px;
	padding-right: 5px;
	border-radius: 5px;
	font-weight: 600;
}

span.keyword {
	background-color: rgb(200,200,200);
	color: black;
	margin-left: 5px;
	margin-right: 5px;
	padding-left: 5px;
	padding-right: 5px;
	border-radius: 5px;
	font-weight: 600;
}

table.tabTable {
	margin: 0px;
	padding: 0px;	
}

span.tabSpan {
	background-color: rgb(230,230,230);
	margin: 5px;
	padding:5px;
	padding-bottom: 20px;
	margin-left: 0px;
	border-right: 1px solid grey;
	border-left: 1px solid grey;
	border-top: 1px solid grey;
	border-top-right-radius: 5px;
	border-top-left-radius: 5px;
	font-size: 18px;
}

span.tabSpanActive {
	background-color: rgb(250,200,200);
	margin: 5px;
	padding:5px;
	padding-bottom: 20px;
	margin-left: 0px;
	border-right: 1px solid grey;
	border-left: 1px solid grey;
	border-top: 1px solid grey;
	border-top-right-radius: 5px;
	border-top-left-radius: 5px;
	font-size: 18px;
	pointer-events:none;
}

div.chartDiv {
	position: absolute;
	width: 800px;
	height: 500px;
	left: 850px;
	top: 0px;
	background-color: rgb(240,240,240);
	border-radius: 10px;
	border: 1px solid rgb(220,220,220);
}

div.genesTab {
	position: absolute;
	top:140px;
	left:0px;
	bottom:0px;
	right:0px;
	display: none;
	background: white;
	border-radius: 10px;
	overflow-y: auto;
}

div.interactionTab {
	position: absolute;
	top:140px;
	left:0px;
	bottom:0px;
	right:0px;
	display: none;
	background: white;
	border-radius: 10px;
	overflow-y: auto;
}

div.ic50Tab {
	position: absolute;
	top:140px;
	left:0px;
	bottom:0px;
	right:0px;
	display: none;
	background: white;
	border-radius: 10px;
	overflow-y: auto;
}

div.wordsTab {
	position: absolute;
	top:140px;
	left:0px;
	bottom:0px;
	right:0px;
	display: none;
	background: white;
	border-radius: 10px;
	overflow-y: auto;
}

div.similarCompoundsTab {
	position: absolute;
	top:140px;
	left:0px;
	bottom:0px;
	right:0px;
	display: none;
	background: white;
	border-radius: 10px;
	overflow-y: auto;
}

div.graph {
	position: absolute;
	width: 700px;
	height: 500px;
	left: 900px;
	top: 0px;
	background-color: rgb(240,240,240);
	border-radius: 10px;
	border: 1px solid rgb(220,220,220);
}

div.ccgraph {
	position: absolute;
	width: 1050px;
	height: 700px;
	left: 900px;
	top: 0px;
	padding: 25px;
	background-color: white;
	border-radius: 10px;
	border: 1px solid rgb(220,220,220);
}

p.empty {
	margin: 10px;
	color: rgb(100,50,50);
}

input.inputField {
	border: 2px solid rgb(120,120,120);
	background-color: rgb(240,230,230);
	padding: 5px;
	margin-right: 20px;
	border-radius: 10px;
}

input.inputButton {
	border: 2px solid rgb(120,120,120);
	background-color: rgb(200,200,255);
	color: rgb(30,30,255);
	padding: 5px;
	margin-right: 20px;
	border-radius: 10px;
	width: 100px;
	font-family: Simple-Line-Icons;
	font-size: 20px;
}

input.inputButton:hover {
	background-color: rgb(30,30,200);
	color: white;
}

.autocomplete {
  /*the container must be positioned relative:*/
  position: relative;
  display: inline-block;
}

.autocomplete-items {
  position: absolute;
  border: 1px solid #d4d4d4;
  border-bottom: none;
  border-top: none;
  z-index: 99;
  /*position the autocomplete items to be the same width as the container:*/
  top: 100%;
  left: 0;
  right: 0;
}
.autocomplete-items div {
  padding: 10px;
  cursor: pointer;
  background-color: #fff;
  border-bottom: 1px solid #d4d4d4;
}
.autocomplete-items div:hover {
  /*when hovering an item:*/
  background-color: #e9e9e9;
}
.autocomplete-active {
  /*when navigating through the items using the arrow keys:*/
  background-color: DodgerBlue !important;
  color: #ffffff;
}

a.pmidLink {
  color: black;
  text-decoration: none;
}

a.pmidLink:hover {
  color: rgb(80,80,150);
}

a.geneLink {
  color: rgb(80,80,150);
  text-decoration: none;
}

a.geneLink:hover {
  color: rgb(150,150,250);
}

td.publicationCell {
	border-bottom: 1px solid grey;
	background: linear-gradient(rgba(255,255,255,1), rgba(245,245,255,1)); 
}

p.publicationTitle {
	text-align: left;
	font-size: 20px;
	margin: 10px;
	padding: 0px;
}

p.publicationJournal {
	text-align: left;
	font-size: 12px;
	margin: 10px;
	margin-top:0px;
	padding: 0px;"
}

p.publicationAbstract {
	text-align: justify;
	margin: 10px;
	margin-top:0px;
	padding: 0px;
	font-family: "Times New Roman", Times, serif;
}

tr.tableRow:hover {
	background-color: rgb(250,200,200);
}

span.logo {
	color: rgb(50,50,100);
	font-size: 50px;
	font-weight: 300;
	text-shadow: 0 0 3px rgb(150,150,255);
	cursor: default;
}

span.tableCellHeader {
	color:rgb(150,150,150);
	font-size: 12px;
}

span.sli {
	font-family: Simple-Line-Icons;
}

input.inputFilterText {
	border: 0px;
	border-bottom: 1px solid black;
}

input:focus {
	outline:none;
	}

input.inputFilterButton {
	font-family: Simple-Line-Icons;
	font-size: 14px;
	border: 1px solid rgb(120,120,120);
	background-color: rgb(200,200,255);
	color: rgb(30,30,255);
	padding: 5px;
	margin-right: 20px;
	border-radius: 7px;
}

input.inputFilterButton:hover {
	background-color: rgb(30,30,200);
	color: white;
}